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난치성 딸꾹질 - review

작성자dcwww|작성시간26.06.22|조회수1 목록 댓글 0

출처: Intractable Hiccups - PubMed

 

Review Curr Neurol Neurosci Rep  2018 Jun 22;18(8):51.

 doi: 10.1007/s11910-018-0856-0.

Intractable Hiccups

Stasia Rouse 1Matthew Wodziak 2

Abstract

Purpose of review: Hiccups are a common problem that crosses multiple disciplines including neurology, gastroenterology and pulmonology, and primary care. There are no formal guidelines to the treatment of intractable hiccups and treatment is based on experience and anecdotal evidence often relying on older medications. We have reviewed the relevant literature with an emphasis on the last five years or so in management of intractable hiccups.

Recent findings: The production of hiccups is a complex mechanism which involves multiple neurotransmitters and anatomical structure within the central and peripheral nervous system. A number of medications and other therapy have been reported successful for intractable hiccups. Intractable hiccups can occur more often than we realize and present to multiple medical disciplines. A number of pharmacologic option have been found to be useful including dopamine-blocking medication, baclofen, and gabapentin along with anticonvulsants.

 

난치성 딸꾹질

 

요약

검토 목적: 딸꾹질은 신경과, 소화기내과, 호흡기내과, 그리고 일차 진료를 포함한 여러 분야에 걸쳐 흔히 발생하는 문제입니다. 난치성 딸꾹질 치료에 대한 공식적인 지침은 없으며, 치료는 경험과 일화적 증거에 기반하고 종종 오래된 약물에 의존합니다. 본 연구에서는 난치성 딸꾹질 관리에 관한 최근 5년 정도의 관련 문헌을 검토했습니다.

최근 연구 결과: 딸꾹질 발생은 중추 및 말초 신경계 내의 여러 신경전달물질과 해부학적 구조가 관여하는 복잡한 기전입니다. 여러 약물과 기타 치료법이 난치성 딸꾹질에 효과적인 것으로 보고되었습니다. 난치성 딸꾹질은 우리가 인식하는 것보다 더 자주 발생하며 다양한 의료 분야의 진료를 필요로 합니다. 도파민 차단제, 바클로펜, 가바펜틴 및 항경련제를 포함한 여러 약물 치료법이 유용한 것으로 밝혀졌습니다.

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